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Oplosbare Antibody Stimulatieter onthuld door BOOST fosfotyrosine Proteomics

Chimère  antigeen  receptor  T-cellen (CAR-T-cellen) de toekomst in immunotherapie voor auto-immuunziekten?

Doelstelling:  CAR-T-celtherapie heeft een revolutie teweeggebracht in de behandeling van oncologische ziekten en recentelijk zijn mogelijke toepassingen bij auto-immuunziekten beschreven. De beoordeling heeft tot doel de beschikbare gegevens over de behandeling met CAR-T-cellen te integreren, met de nadruk op auto-immuunziekten, om de therapeutische vooruitgang en hun mogelijke toekomstige klinische toepasbaarheid bij auto-immuniteit te bepalen.

Materialen en methoden:  Er is gezocht in PubMed met de trefwoorden “Chimeric Antigen Receptor” en “CART cell”. De relevante documenten werden geselecteerd en de informatie werd kritisch bekeken.

Resultaten:  Bij de behandeling van auto-immuunziekten zijn in preklinische modellen drie verschillende cellulaire strategieën gebruikt, waaronder chimere antigeenreceptor T-cellen, chimere auto-antilichaamreceptor T-cellen en chimere antigeenreceptor in regulerende T-lymfocyten . Alle drie soorten therapie zijn effectief geweest. De mogelijke nadelige effecten daarin, het cytokine-afgiftesyndroom, cellulaire toxiciteit en neurotoxiciteit moeten altijd in gedachten worden gehouden.

Conclusies:  Hoewel er nog geen informatie over mensen beschikbaar is, laten preklinische modellen van CAR-T-cellen bij de behandeling van auto-immuunziekten veelbelovende resultaten zien, zodat ze in de toekomst een nuttige en effectieve therapie kunnen worden bij de behandeling van deze pathologieën.

Ovalbumine  Antigen -Specifieke Activatie van menselijke T-cel  -receptor  lijkt sterk op Oplosbare Antibody Stimulatieter onthuld door BOOST fosfotyrosine Proteomics

Activering van de T-celreceptor (TCR) leidt tot een netwerk van vroege signalering, voornamelijk georkestreerd door tyrosinefosforylering in T-cellen. De TCR wordt gewoonlijk geactiveerd met behulp van oplosbare anti-TCR-antilichamen, maar deze benadering is niet antigeenspecifiek. Als alternatief wordt aangenomen dat het activeren van de TCR met behulp van specifieke antigenen met een reeks bindingsaffiniteiten in de vorm van een peptide-major histocompatibiliteitscomplex (pMHC) meer fysiologisch is. Vanwege het ontbreken van grootschalige fosfotyrosine (pTyr) proteomische onderzoeken die anti-TCR-antilichamen en pMHC rechtstreeks vergelijken, blijft een uitgebreide definitie van deze geactiveerde toestanden echter raadselachtig.

Opheldering van het tyrosinefosfoproteoom met behulp van kwantitatieve pTyr-proteomics maakt een beter begrip mogelijk van de unieke kenmerken van deze activerende middelen en de rol van ligandbindingsaffiniteit op signalering. Hier passen we de latest opgerichte breedspectrumoptimalisatie van selectieve triggering (BOOST) toe om verstoringen in tyrosinefosforylering van menselijke TCR te onderzoeken, veroorzaakt door anti-TCR-antilichamen en pMHC. Onze gegevens laten zien dat pMHC-activering met hoge affiniteit ovalbumine (OVA) van de menselijke TCR een grotendeels vergelijkbare, zij het mogelijk sterkere, pTyr-gemedieerdesignaalregulerende as vergeleken met het anti-TCR-antilichaam. De signaleringsoutput die resulteert uit OVA pMHC-varianten correleert goed met hun zwakkere affiniteiten, waardoor affiniteit-afstembare controle van de signaalsterkte mogelijk is. Gezamenlijk bieden we een raamwerk voor het toepassen van BOOST om pTyr-gemedieerde signaalroutes van menselijke T-cellen te vergelijken die op een antigeenonafhankelijke en antigeenspecifieke manier zijn geactiveerd.

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tminederland

HIV-1 p24 ELISA Kit

Z7040001 1 kit
EUR 974.4
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

HIV-1 p24

E5-00024 1mg
EUR 1152

HIV-1 p24

E62H002 100ug
EUR 458.4

HIV Type 1 p24 Antigen ELISA (96 Determinations)

0801111 96T
EUR 657.79
Description: Please contact Gentaur in order to receive the datasheet of the product.

HIV Type 1 p24 Antigen ELISA (96 Determinations)

801111 96 Determinations
EUR 591

HIV Type 1 p24 Antigen ELISA 2.0 (96 Determinations)

801002 96 Determinations
EUR 574

HIV Type 1 p24 Antigen ELISA 2.0 (96 Determinations)

0801002 96T
EUR 603

HIV type 1 P24

DAG1520 100 µg
EUR 972

HIV-1 p24 Antibody

7313-002mg 0.02 mg
EUR 206.18
Description: HIV-1 p24 Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix. The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein. The p24 is the major capsid protein of the virus and has been used in clinical trials as one of the components of the HIV-1 vaccine because of the high degree of sequence conservation between different strains.

HIV-1 p24 Antibody

7313-01mg 0.1 mg
EUR 523.7
Description: HIV-1 p24 Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix. The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein. The p24 is the major capsid protein of the virus and has been used in clinical trials as one of the components of the HIV-1 vaccine because of the high degree of sequence conservation between different strains.

Recombinant HIV-1 p24

7-07603 100µg Ask for price

Recombinant HIV-1 p24

7-07604 500µg Ask for price

Recombinant HIV-1 p24

7-07605 1000µg Ask for price

HIV-1 Gag p24

05-005 50 ug
EUR 434.4
Description: The HIV-1 Gag p24 is available in Europe and for worldwide shipping via Gentaur.

HIV-1 Gag p24

05-006 250 ug
EUR 1154.4
Description: The HIV-1 Gag p24 is available in Europe and for worldwide shipping via Gentaur.

HIV-1, p24 Protein

abx069857-1mg 1 mg
EUR 1888.8

HIV-1 p24 Protein

abx169032-1mg 1 mg
EUR 661.2

HIV-1 p24 Antibody

20-abx137062
  • EUR 427.20
  • EUR 627.60
  • 0.5 mg
  • 1 mg

HIV-1 p24 Antibody

abx021869-1mg 1 mg
EUR 794.4

HIV-1 p24 Antibody

abx021870-1mg 1 mg
EUR 760.8

HIV-1 p24 Antibody

abx021871-1mg 1 mg
EUR 794.4

HIV-1 p24 Antibody

abx021872-1mg 1 mg
EUR 794.4

HIV-1 p24 Antibody

abx021873-1mg 1 mg
EUR 794.4

HIV-1 p24 Antibody

abx021882-1mg 1 mg
EUR 1178.4

HIV-1 p24 Antibody

abx021883-1mg 1 mg
EUR 1220.4

HIV-1 p24 Antibody

abx021886-1mg 1 mg
EUR 1220.4

HIV-1 p24 Antibody

abx021887-1mg 1 mg
EUR 1220.4

HIV-1 p24 Antibody

abx021888-1mg 1 mg
EUR 1220.4

HIV-1 p24 Antibody

abx023027-1ml 1 ml
EUR 693.6

HIV 1 p24 Protein

abx060589-1mg 1 mg
EUR 1545.6

HIV-1 p24 Protein

abx061424-05mg 0.5 mg
EUR 886.8

HIV-1 p24 Antibody

abx023925-1mg 1 mg
EUR 828

HIV-1 p24 Antibody

abx023926-1mg 1 mg
EUR 828

HIV-1 p24 Protein

20-abx261886
  • EUR 5388.00
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

p24-HIV(p24/661) Antibody

BNCA0661-250 250uL
EUR 459.6
Description: Primary antibody against p24-HIV(p24/661), APC conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNCAP0661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNCAP0661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC610661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF660R conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC610661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF660R conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNCR0661-250 250uL
EUR 459.6
Description: Primary antibody against p24-HIV(p24/661), RPE conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNUB0661-100 100uL
EUR 250.8
Description: Primary antibody against p24-HIV(p24/661), Concentration: 0.2mg/mL

p24-HIV(p24/661) Antibody

BNUB0661-500 500uL
EUR 549.6
Description: Primary antibody against p24-HIV(p24/661), Concentration: 0.2mg/mL

p24-HIV(p24/661) Antibody

BNC430661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF543 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC430661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF543 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC400661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF640R conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC400661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF640R conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC880661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF488A conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC880661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF488A conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC810661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF680R conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC810661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF680R conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNCH0661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNCH0661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNCP0661-250 250uL
EUR 459.6
Description: Primary antibody against p24-HIV(p24/661), PerCP conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNUM0661-50 50uL
EUR 474
Description: Primary antibody against p24-HIV(p24/661), 1mg/mL

p24-HIV(p24/661) Antibody

BNC050661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF405M conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC050661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF405M conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC680661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF568 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC680661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF568 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC700661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF770 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC700661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF770 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC800661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF680 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC800661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF680 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNCB0661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), Biotin conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNCB0661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), Biotin conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC940661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF594 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC940661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF594 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC550661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF555 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC550661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF555 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC470661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF647 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC470661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF647 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC040661-100 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF405S conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC040661-500 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF405S conjugate, Concentration: 0.1mg/mL

HIV p24 Antibody

abx021867-1mg 1 mg
EUR 1612.8

HIV p24 Antibody

abx021868-1mg 1 mg
EUR 1612.8

Human(HIV-P24)

QY-E05679 96T
EUR 433.2

HIV Type 1 p24 Antigen ELISA (5 X 96 Determinations)

801200 5 X 96 Determinations
EUR 2330

HIV Type 1 p24 Antigen ELISA (5 X 96 Determinations)

0801200 5 X 96T
EUR 2543.52
Description: Please contact Gentaur in order to receive the datasheet of the product.

Custom Antibody titration by ELISA up to 2 rabbits and 1 bleed

ELISA-1 1
EUR 242.4

HIV type 1 P24 [His]

DAG2375 100 µg
EUR 868.8

HIV type 1 P24 [His]

DAG2377 100 µg
EUR 868.8

HIV type 1 p24 [FITC]

DAGH004 50 Tests
EUR 1112.4

HIV type 1 P24 [GST]

DAG1516 100 µg
EUR 774

HIV type 1 P24 [His]

DAG1518 100 µg
EUR 774

HIV type 1 P24 [Biotin]

DAG1519 100 µg
EUR 972

HIV type 1 P24 [His]

DAG1799 50 ug
EUR 2017.2

HIV-1 p24 Recombinant Protein

53-341 0.01 mg
EUR 789.9
Description: HIV-1 p24 Recombinant Protein

Recombinant HIV-1 p24 Core

7-07597 100µg Ask for price

Recombinant HIV-1 p24 Core

7-07598 500µg Ask for price

Recombinant HIV-1 p24 Core

7-07599 1000µg Ask for price

Recombinant HIV-1 p24 , 24kDa

7-07621 2µg Ask for price

Recombinant HIV-1 p24 , 24kDa

7-07622 10µg Ask for price

Recombinant HIV-1 p24 , 24kDa

7-07623 100µg Ask for price

HIV 1 / 2 p24 Antibody

abx021866-1mg 1 mg
EUR 1212

HIV-1 p24 Antibody (FITC)

abx021884-100ug 100 ug
EUR 886.8

HIV 1 / 2 p24 Antibody

abx021890-1mg 1 mg
EUR 1212

HIV-1 p24 Antibody (FITC)

abx023026-1ml 1 ml
EUR 678

HIV-1 p24 Antibody (Biotin)

abx023028-1ml 1 ml
EUR 794.4

HIV-1 p24 Antibody (HRP)

abx023029-1ml 1 ml
EUR 886.8

HIV-1 p24 Core Protein

20-abx260141
  • EUR 1062.00
  • EUR 410.40
  • EUR 1646.40
  • 0.5 mg
  • 100 ug
  • 1 mg

Polyclonal HIV-1 p24 Antibody

APR11116G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HIV-1 p24 . This antibody is tested and proven to work in the following applications:

HIV-1 p24, His tag

E410A26-20 20μg
EUR 520.8

HIV-1 p24 Antibody [8G9]

PM-6335-002mg 0.02 mg
EUR 206.18
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

HIV-1 p24 Antibody [8G9]

PM-6335-01mg 0.1 mg
EUR 523.7
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

HIV-1 p24 Antibody [7F4]

PM-6585-002mg 0.02 mg
EUR 206.18
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

HIV-1 p24 Antibody [7F4]

PM-6585-01mg 0.1 mg
EUR 523.7
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

Anti-HIV-1 p24 Antibody

STJ60071 100 µg
EUR 508.8

Anti-HIV-1 p24 Antibody

STJ60072 100 µg
EUR 508.8

HIV Type-1 p24 Antibody

V2344-100UG 100 ug
EUR 499
Description: Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load.

HIV Type-1 p24 Antibody

V2344-20UG 20 ug
EUR 219
Description: Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load.

HIV Type-1 p24 Antibody

V2344CF488-100T 100 Tests
EUR 499
Description: Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load.

HIV Type-1 p24 Antibody

V2344SAF-100UG 100 ug
EUR 499
Description: Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load.

Human HIV(1+2 antibodies plus p24 antigen (4th Generation) ELISA Kit

EH4101 96T
EUR 571.5
Description: Method of detection: Qualitative ;Reacts with: Homo sapiens;Sensitivity: Qualitative

HIV Type 1 p24 Antigen ELISA 2.0 (5 X 96 Determinations)

0801008 5 X 96T
EUR 2543.52
Description: Please contact Gentaur in order to receive the datasheet of the product.

HIV Type 1 p24 Antigen ELISA 2.0 (5 X 96 Determinations)

801008 5 X 96 Determinations
EUR 2386

HIV-1 p24 Immune Complex Dissociation Kit

Z7040009 1 kit
EUR 207.6
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

Anti-HIV p24 antibody

10-2842 1 mg
EUR 360
Description: Anti-HIV p24 Ag monoclonal antibody

Anti-HIV p24 antibody

10-2843 1 mg
EUR 360
Description: Anti-HIV p24 Ag monoclonal antibody

Anti-HIV p24 antibody

10-2844 1 mg
EUR 360
Description: Anti-HIV p24 Ag monoclonal antibody

Anti-HIV p24 antibody

10-2845 1 mg
EUR 360
Description: Anti-HIV p24 Ag monoclonal antibody

QuickTiter HIV Lentivirus Quantitation Kit (p24 ELISA)

VPK-108-H 96 assays
EUR 866.4
Description: Quantitation of the HIV-1 p24 core protein of a lentiviral vector is an efficient, well-published method for determining lentivirus physical titer. The QuickTiter Lentivirus Quantitation Kits provide a convenient method of p24 antigen quantitation.

QuickTiter HIV Lentivirus Quantitation Kit (p24 ELISA)

VPK-108-H-5 5 x 96 assays
EUR 3560.4
Description: Quantitation of the HIV-1 p24 core protein of a lentiviral vector is an efficient, well-published method for determining lentivirus physical titer. The QuickTiter Lentivirus Quantitation Kits provide a convenient method of p24 antigen quantitation.

HIV type 1 P24 (HXBc2) [His]

DAG2376 100 µg
EUR 868.8

HIV type 1 P24 (p24HXBc2) [His]

DAG2378 100 µg
EUR 1095.6

HIV type 1 P24 (CN54) [His]

DAG2380 100 µg
EUR 1095.6

Recombinant HIV-1 p24 Core, Sf9

7-07600 2µg Ask for price

Recombinant HIV-1 p24 Core, Sf9

7-07601 10µg Ask for price

Recombinant HIV-1 p24 Core, Sf9

7-07602 100µg Ask for price

Recombinant HIV-1 p24 His Tag

7-07606 5µg Ask for price

Recombinant HIV-1 p24 His Tag

7-07607 20µg Ask for price

Recombinant HIV-1 p24 His Tag

7-07608 1mg Ask for price

Recombinant HIV-1 p24, Biotin Labeled

7-07612 100µg Ask for price

Recombinant HIV-1 p24, Biotin Labeled

7-07613 500µg Ask for price

Recombinant HIV-1 p24, Biotin Labeled

7-07614 1000µg Ask for price

Recombinant HIV-1 gag p17, p24

7-07675 100µg Ask for price

Recombinant HIV-1 gag p17, p24

7-07676 500µg Ask for price

Recombinant HIV-1 gag p17, p24

7-07677 1000µg Ask for price

Mouse antibody for HIV-1 p24

1941 100 ug
EUR 399.3
Description: This is purified Mouse monoclonal antibody against HIV-1 p24 for WB, ELISA.

Mouse antibody for HIV-1 p24

1946 100 ug
EUR 425.4
Description: This is purified Mouse monoclonal antibody against HIV-1 p24 for WB, ELISA.

Mouse antibody for HIV-1 p24

1947 100 ug
EUR 425.4
Description: This is purified Mouse monoclonal antibody against HIV-1 p24 for WB, ELISA.

Mouse antibody for HIV-1 p24

1948 100 ug
EUR 425.4
Description: This is purified Mouse monoclonal antibody against HIV-1 p24 for WB, ELISA.

Mouse antibody for HIV-1 p24

1949 100 ug
EUR 425.4
Description: This is purified Mouse monoclonal antibody against HIV-1 p24 for WB, ELISA.

HIV-1 gag p24 IIIB Protein

abx060586-05mg 0.5 mg
EUR 1128

HIV-1 p24 Core, Sf9 Protein

20-abx260012
  • EUR 2815.20
  • EUR 493.20
  • EUR 276.00
  • 100 ug
  • 10 ug
  • 2 µg

HIV-1 gag p17, p24 Protein

20-abx260277
  • EUR 1062.00
  • EUR 410.40
  • EUR 1930.80
  • 0.5 mg
  • 100 ug
  • 1 mg

HIV-1 p24, Biotin Labeled Protein

20-abx260358
  • EUR 1496.40
  • EUR 560.40
  • EUR 2364.00
  • 0.5 mg
  • 100 ug
  • 1 mg

HIV-1 p24, 24 kDa Protein

20-abx263118
  • EUR 1562.40
  • EUR 393.60
  • EUR 276.00
  • 100 ug
  • 10 ug
  • 2 µg

Polyclonal HIV-1 p24 Antibody [7F4]

APR11117G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Mouse that recognizes and binds to Human HIV-1 p24 [7F4] . This antibody is tested and proven to work in the following applications:

HIV-1 p24 Antibody [8G9] (biotin)

PM-6335-biotin-002mg 0.02 mg
EUR 206.18
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

HIV-1 p24 Antibody [8G9] (biotin)

PM-6335-biotin-01mg 0.1 mg
EUR 523.7
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

HIV-1 p24 Antibody [8G9] (HRP)

PM-6335-HRP-002mg 0.02 mg
EUR 206.18
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

HIV-1 p24 Antibody [8G9] (HRP)

PM-6335-HRP-01mg 0.1 mg
EUR 523.7
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

HIV-1 p24 Antibody [7F4] (biotin)

PM-6585-biotin-002mg 0.02 mg
EUR 206.18
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

HIV-1 p24 Antibody [7F4] (biotin)

PM-6585-biotin-01mg 0.1 mg
EUR 523.7
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

HIV-1 p24 Antibody [7F4] (HRP)

PM-6585-HRP-002mg 0.02 mg
EUR 206.18
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

HIV-1 p24 Antibody [7F4] (HRP)

PM-6585-HRP-01mg 0.1 mg
EUR 523.7
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

Recombinant HIV-1 p24 Protein [His]

VAng-0527Lsx-inquire inquire Ask for price
Description: HIV type 1 P24 Antigen, recombinant protein from insect cell expression system.

Recombinant HIV-1 P24 Protein (Gorillas)

VAng-Lsx0245-1mg 1 mg
EUR 3058.8
Description: HIV type 1 P24 (Antigen), recombinant protein from E. coli.

Monoclonal Mouse Anti-Hiv(P24)

C010105-10mg 10mg
EUR 1641.6

Monoclonal Mouse Anti-Hiv(P24)

C010105-1mg 1mg
EUR 322.8

Recombinant HIV-I p24 gag

7-07618 100µg Ask for price

Recombinant HIV-I p24 gag

7-07619 500µg Ask for price

Recombinant HIV-I p24 gag

7-07620 1000µg Ask for price

anti-HIV p24 Monoclonal antibody

012-A-01mg 0,1 mg
EUR 321
Description: anti-HIV-1 p24 IgG1 (monoclonal) Produced against a recombinant protein.

anti-HIV p24 Monoclonal antibody

012-A-1000ug 1000 ug
EUR 1539
Description: anti-HIV-1 p24 IgG1 (monoclonal) Produced against a recombinant protein.

HIV-I p24 gag Protein

20-abx260279
  • EUR 1062.00
  • EUR 410.40
  • EUR 1930.80
  • 0.5 mg
  • 100 ug
  • 1 mg

Anti-HIV p24 protein antibody

STJ16100518 100 µg
EUR 487.2

Anti-HIV/p24 monoclonal Antibody

A1020-100 each
EUR 444

Goat Anti-HIV-1 p24 Polyclonal Antibody

DPAB0249 1 ml
EUR 781.2

Goat Anti-HIV-1 p24 Polyclonal Antibody

DPAB0250 1 ml
EUR 826.8

Goat Anti-HIV-1 p24 Polyclonal Antibody

DPAB0251 1 ml
EUR 1146

HIV-1 gag Protein p24 (137-154)

5-01316 4 x 1mg Ask for price

HIV-1 gag Protein p24 (194-210)

5-01317 4 x 1mg Ask for price

Recombinant HIV-1 p24 gag, His Tag

7-07609 100µg Ask for price

Recombinant HIV-1 p24 gag, His Tag

7-07610 500µg Ask for price

Recombinant HIV-1 p24 gag, His Tag

7-07611 1000µg Ask for price

Recombinant HIV-1 p24, Horseradish Peroxidase Labeled

7-07615 100µg Ask for price

Recombinant HIV-1 p24, Horseradish Peroxidase Labeled

7-07616 500µg Ask for price

Recombinant HIV-1 p24, Horseradish Peroxidase Labeled

7-07617 1000µg Ask for price

Recombinant HIV-1 gag p17, p24, gp120

7-07678 100µg Ask for price

Recombinant HIV-1 gag p17, p24, gp120

7-07679 500µg Ask for price

Recombinant HIV-1 gag p17, p24, gp120

7-07680 1000µg Ask for price

Anti-Capsid protein p24 (HIV-1) Purified

11-327-C025 0.025 mg
EUR 135.6

Anti-Capsid protein p24 (HIV-1) Purified

11-327-C100 0.1 mg
EUR 223.2

Mouse Monoclonal Anti- HIV-1 p24 IgG

AB-15210 100 ug
EUR 416.4

HIV-1 gag p17, p24, gp120 Protein

20-abx260274
  • EUR 1062.00
  • EUR 410.40
  • EUR 1930.80
  • 0.5 mg
  • 100 ug
  • 1 mg

HIV-1 p24, Horseradish Peroxidase Labeled Protein

20-abx260359
  • EUR 1496.40
  • EUR 560.40
  • EUR 2364.00
  • 0.5 mg
  • 100 ug
  • 1 mg

HIV-1 gag Protein p24 (194-210)

H-2986.0500 0.5mg
EUR 327.6
Description: Sum Formula: C73H126N20O23S; CAS# [141281-67-6]

HIV-1 gag Protein p24 (194-210)

H-2986.1000 1.0mg
EUR 559.2
Description: Sum Formula: C73H126N20O23S; CAS# [141281-67-6]

HIV-1 gag Protein p24 (137-154)

H-3006.0500 0.5mg
EUR 327.6
Description: Sum Formula: C92H158N26O26S; CAS# [198636-98-5]

HIV-1 gag Protein p24 (137-154)

H-3006.1000 1.0mg
EUR 559.2
Description: Sum Formula: C92H158N26O26S; CAS# [198636-98-5]

Bilaterale anterior cerebrale slagader occlusie na CD19- en BCMA-gerichte chimere  antigeen  receptor  van T-celtherapie voor een patiënt myeloom

Chimere antigeenreceptor T (CAR-T)-celtherapie is een veelbelovende behandeling voor recidiverend/refractair multipel myeloom (RRMM). In ons vorige rapport was CD19- en BCMA-gerichte gelijktijdige toediening van CAR-T geassocieerd met een hoog responspercentage. Hoewel cytokine launch syndrome (CRS) en neurotoxiciteit frequente complicaties zijn na behandeling met CAR-T, wordt een herseninfarct zelden gerapporteerd als een CAR-T-gerelateerde complicatie. We rapporteerden een 73-jarige vrouwelijke MM-patiënt die CD19- en BCMA-gerichte CAR-T ontving voor refractaire ziekte.

Haar ziekte reageerde op CAR-T- therapie, maar ze ontwikkelde neurologische symptomen na CRS. Craniale CT en MRI toonden meerdere herseninfarcten en bilaterale anterieure cerebrale arterie (ACA) occlusie aan. We suggereren dat een ander herseninfarct dan CAR-T-gerelateerde neurotoxiciteit de onderliggende oorzaak is van abnormale neuropsychologische symptomen, en diagnostische beeldvormingstests moeten actief worden uitgevoerd om ischemische cerebrovasculaire gebeurtenissen uit te sluiten.

Het intracellulaire domein van CD40 is een krachtige Costimulatoire Ingredient in chimère  Antigen  Receptoren

De co-stimulerende domeinen die zijn ingebouwd in chimere antigeenreceptoren (CAR’s) van de tweede generatie en de derde generatie, hebben een sterke invloed op de functie van CAR-T-cellen . Hier hebben we CAR’s van de tweede generatie en de derde generatie onderzocht die het signaleringsdomein van de CD40-receptor herbergen als een nieuw costimulerend component in vergelijking met vergelijkbare CAR’s die het 4-1BB-domein dragen . In CAR’s van beide generaties was CD40 krachtiger dan 4-1BB bij het triggeren van de NF-KB-signaleringsroute.

In humane T-cellen van 2 donoren was CD40 vergelijkbaar met 4-1BB bij het opreguleren van co-stimulerende en activatiemarkers, het induceren van pro-inflammatoire cytokinesecretie en het mediëren van het doden van doelwitcellen. Interessant genoeg waren er duidelijk verschillen in het responspatroon van T-cellen van de 2 donoren met betrekking tot CD40 en 4-1BB. We concluderen dat in menselijke T-cellen het CD40- signaleringsdomein een krachtig co-stimulerend component is in CAR’s van zowel de tweede generatie als de derde generatie.

Een systematische herziening van de rol van chimere  Antigeen  Receptor  T (CAR-T) celtherapie bij de behandeling van solide tumoren

Chimere antigeenreceptor T (CAR-T) celtherapie maakt gebruik van de eigen T-lymfocyten van de patiënt die zijn ontworpen om kankercellen aan te vallen. Het is door de Meals and Drug Administration (FDA) goedgekeurd voor verschillende hematologische maligniteiten en wordt momenteel geëvalueerd bij solide kankers in vroege fase-onderzoeken. We deden een systematische evaluate bestaande uit 15 prospectieve klinische onderzoeken (n = 159) die CAR-T-cellen in solide kankers evalueerden . Vroege fase-onderzoeken toonden veelbelovende responspercentages bij ovariumepitheelkanker (100%), humaan epidermale groeifactorreceptor  (HER2)-positief sarcoom (67%) , epidermale groeifactorreceptor (EGFR)-positieve galwegkanker (65%), gevorderde maag-/pancreaskanker (82%), hepatocellulair carcinoom (67%),en colorectale kanker (70%) .

De mediane algehele respons voor alle maligniteiten was 62% (bereik 17%-100%) . De mediane progressievrije overleving en de totale overleving werden in de meeste onderzoeken niet bereikt. Cytokine-afgiftesyndroom werd gezien bij slechts één patiënt met cholangiocarcinoom die EGFR-specifieke CAR-T-celtherapie kreeg. Hoewel de overlevingsgegevens nog steeds niet volgroeid zijn, liet CAR-T-celtherapie bij solide maligniteiten bemoedigende responspercentages zien en werd goed verdragen.

Verschillen in lymfoompatiënten tussen chimeer  antigeen  receptor  van T-cel therapeutische proeven en bevolking

Chimere antigeenreceptor (CAR)-T-celtherapieën lijken veelbelovende behandelingen te zijn voor non-Hodgkin- en B-cellymfoom. Verschillende CAR-T-therapieën die zijn goedgekeurd door de Amerikaanse Meals and Drug Administration, zijn echter alleen op werkzaamheid getest in relatief weinig klinische onderzoeken met een enkele arm met kleine steekproefomvang. We probeerden de verschillen tussen patiënten in deze onderzoeken en de algemene populatie van patiënten met non-Hodgkin- en B-cellymfoom te onderzoeken. Vijfhonderdtweeëntwintig patiënten uit 15 CAR-T-onderzoeken gevonden in een systematische evaluate en 417.492 patiënten uit de Surveillance, Epidemiology, and Finish Outcomes (SEER) Program-database werden vergeleken.

De deelnemers aan de CAR-T-studie leken jonger (46,7% jonger dan 70 jaar vs. 42,2%) , meer mannelijk (68,0% vs. 55,7%) en werden gedurende een kortere periode gevolgd in vergelijking met patiënten in de SEER-populatie (gemiddelde [M] 45,6 maanden, 95% betrouwbaarheidsinterval [BI] 17,7 tot 63,three maanden follow-up vs. M 57,1 maanden, 95% BI 57,Zero tot 57,three maanden overleving). Deelnemers aan de CAR-T-studie kunnen aanzienlijk verschillen van de algemene populatie van patiënten met non-Hodgkin- en B-cellymfoom . De effectiviteit van CAR-T-therapieën bij de algemene populatie van lymfoompatiënten kan verschillen van de effectiviteit die is aangetoond in onderzoeken. Nieuw gecreëerde CAR-T-patiëntenregisters zijn essentieel om de effectiviteit van de therapieën op populatieniveau huge te stellen.

 

Adenosine Kinase Inhibitor (hydrate)

C5282-1 1 mg
EUR 134.4
Description: IC50: 1.7 nM in cell-free assaysAdenosine Kinase Inhibitor is an inhibitor of adenosine kinase. Adenosine kinase is the key metabolizing enzyme regulating cellular adenosine concentrations.

DiscoveryProbe? Kinase Inhibitor Library

L1024-.1 100 uL/well(10 mM solution)
EUR 7520.4

IKK-? Kinase Inhibitor II

1811-1 each
EUR 189.6

VEGFR Tyrosine Kinase Inhibitor II

C4603-1 1 mg
EUR 141.6

DiscoveryProbe? Tyrosine Kinase Inhibitor Library

L1028-.1 100 uL/well(10 mM solution)
EUR 6476.4

Kinase inhibitor-1

HY-43533 5mg
EUR 680.4

ET-1/ Rat ET- 1 ELISA Kit

ELA-E0482r 96 Tests
EUR 1063.2

HPGDS inhibitor 1

B1046-1 1 mg
EUR 217.2
Description: HPGDS inhibitor 1 is an oral potent and selective inhibitor of hematopoietic prostaglandin D synthase (HPGDS) with IC50 value of 0.7nM [1].Prostaglandin D2 (PGD2) is a mediator of allergy and inflammation.

TAO Kinase inhibitor 1

HY-112136 50mg
EUR 955.2

MAPKII Kinase Inhibitor (Hsp25 Kinase Inhibitor)

SIH-120A 1 mg
EUR 214.8
Description: The substance MAPKII Kinase Inhibitor is a hsp25 kinase inhibitor. It is synthetically produced and has a purity of >95%. The pure substance is white solid which is soluble in DMSO or H20.

ET-1 Polyclonal Antibody

41562-100ul 100ul
EUR 302.4

ET-1 Polyclonal Antibody

41562-50ul 50ul
EUR 224.4

ET-1 Polyclonal Antibody

ABP52878-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of ET-1 from Human. This ET-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human ET-1

ET-1 Polyclonal Antibody

ABP52878-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of ET-1 from Human. This ET-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human ET-1

ET-1 Polyclonal Antibody

ABP52878-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of ET-1 from Human. This ET-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human ET-1

ET-1 Polyclonal Antibody

ES3877-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against ET-1 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

ET-1 Polyclonal Antibody

ES3877-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against ET-1 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Anti-ET-1 antibody

STJ96512 200 µl
EUR 236.4
Description: Rabbit polyclonal to ET-1.

Rabbit Endothelin 1, ET-1 ELISA Kit

1-CSB-E06951Rb
  • EUR 1160.40
  • EUR 7110.00
  • EUR 3760.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rabbit Endothelin 1, ET-1 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

rat Endothelin 1, ET-1 ELISA Kit

1-CSB-E06979r
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring rat Endothelin 1, ET-1 in samples from serum, plasma, cell lysates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Dog Endothelin 1, ET-1 ELISA Kit

1-CSB-E07002c
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Dog Endothelin 1, ET-1 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Endothelin 1, ET-1 ELISA Kit

1-CSB-E07007h
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Endothelin 1, ET-1 in samples from serum, cell culture supernates, urine, saliva. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Endothelin 1, ET-1 ELISA Kit

1-CSB-E05145m
  • EUR 1135.20
  • EUR 6938.40
  • EUR 3672.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Endothelin 1, ET-1 in samples from serum, plasma, cell culture supernates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Pig endothelin 1, ET-1 ELISA Kit

1-CSB-E06806p
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Pig endothelin 1, ET-1 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Cyclin-dependent kinase inhibitor 1 (CDKN1A)

1-CSB-EP005086HU
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Cyclin-dependent kinase inhibitor 1(CDKN1A) expressed in E.coli

Endothelin 1 (ET-1) Antibody

abx024086-100ug 100 ug
EUR 1128

Sorafenib (Raf-1 kinase inhibitor)

SIH-476-10MG 10 mg
EUR 145.2
Description: The substance Sorafenib is a raf-1 kinase inhibitor. It is synthetically produced and has a purity of >99%. The pure substance is off white powder which is soluble inDMSO (200mg/ml) or ethanol (3mg/ml).

Sorafenib (Raf-1 kinase inhibitor)

SIH-476-50MG 50 mg
EUR 346.8
Description: The substance Sorafenib is a raf-1 kinase inhibitor. It is synthetically produced and has a purity of >99%. The pure substance is off white powder which is soluble inDMSO (200mg/ml) or ethanol (3mg/ml).

p16-INK4a Cyclin-Dependent Kinase Inhibitor 2A Human Recombinant Protein

PROTP42771-1 Regular: 20ug
EUR 380.4
Description: CDKN2A Human Recombinant produced in E.Coli, it's a single non-glycosylated polypeptide chain containing 156 amino acids, approximately 16.5 kDa.;CDKN2A is purified by proprietary chromatographic techniques.

187-1, N-WASP inhibitor

B5251-1 1 mg
EUR 478.8

AKT Kinase Inhibitor

A3150-10 10 mg
EUR 1363.2
Description: AKT Kinase Inhibitor

AKT Kinase Inhibitor

A3150-5 5 mg
EUR 819.6
Description: AKT Kinase Inhibitor

AKT Kinase Inhibitor

A3150-5.1 10 mM (in 1mL DMSO)
EUR 895.2
Description: AKT Kinase Inhibitor

MAPKII Kinase Inhibitor

abx076811-1mg 1 mg
EUR 376.8

Tie2 kinase inhibitor

A5979-100 100 mg
EUR 1452
Description: IC50: A reversible and selective inhibitor of Tie2 with IC50 of 0.25 M, whose selectivity is 200-fold higher than that of p38.

Tie2 kinase inhibitor

A5979-25 25 mg
EUR 477.6
Description: IC50: A reversible and selective inhibitor of Tie2 with IC50 of 0.25 M, whose selectivity is 200-fold higher than that of p38.

Tie2 kinase inhibitor

A5979-5 5 mg
EUR 199.2
Description: IC50: A reversible and selective inhibitor of Tie2 with IC50 of 0.25 M, whose selectivity is 200-fold higher than that of p38.

Tie2 kinase inhibitor

A5979-5.1 10 mM (in 1mL DMSO)
EUR 536.4
Description: IC50: A reversible and selective inhibitor of Tie2 with IC50 of 0.25 M, whose selectivity is 200-fold higher than that of p38.

Tie2 kinase inhibitor

E1KS1577 10mg
EUR 1849.2

AKT Kinase Inhibitor

HY-10249A 10mg
EUR 1052.4

Tyrosine kinase inhibitor

HY-10421 25mg
EUR 459.6

Dasatinib (Kinase inhibitor)

SIH-440-25MG 25 mg
EUR 238.8
Description: The substance Dasatinib is a kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is crystalline solid which is soluble in DMSO (200 mg/ml), ethanol (very poorly ), and water (very poorly ).

Dasatinib (Kinase inhibitor)

SIH-440-5MG 5 mg
EUR 160.8
Description: The substance Dasatinib is a kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is crystalline solid which is soluble in DMSO (200 mg/ml), ethanol (very poorly ), and water (very poorly ).

K252A (Kinase inhibitor)

SIH-455-100UG 100 µg
EUR 157.2
Description: The substance K252A is a kinase inhibitor. It is nonomuraea longicatena and has a purity of ?98%. The pure substance is white solid which is soluble to 25 mM in DMSO.

K252A (Kinase inhibitor)

SIH-455-1MG 1 mg
EUR 358.8
Description: The substance K252A is a kinase inhibitor. It is nonomuraea longicatena and has a purity of ?98%. The pure substance is white solid which is soluble to 25 mM in DMSO.

K252B (Kinase inhibitor)

SIH-456-100UG 100 µg
EUR 218.4
Description: The substance K252B is a kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white solid which is soluble in DMSO (1 mg/ml) or dimethyl formamide (1 mg/ml).

K252B (Kinase inhibitor)

SIH-456-1MG 1 mg
EUR 682.8
Description: The substance K252B is a kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white solid which is soluble in DMSO (1 mg/ml) or dimethyl formamide (1 mg/ml).

Midostaurin (Kinase inhibitor)

SIH-468-1MG 1 mg
EUR 205.2
Description: The substance Midostaurin is a kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white to off-white powder which is soluble in DMSO (15 mg/ml), MDC (10 mg/ml), methanol (5 mg/ml) or 100% ethanol (2.5 mg/ml).

Midostaurin (Kinase inhibitor)

SIH-468-5MG 5 mg
EUR 608.4
Description: The substance Midostaurin is a kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white to off-white powder which is soluble in DMSO (15 mg/ml), MDC (10 mg/ml), methanol (5 mg/ml) or 100% ethanol (2.5 mg/ml).

Tie2 Kinase Inhibitor

B1338-25 each
EUR 907.2

Tie2 Kinase Inhibitor

B1338-5 each
EUR 314.4

YAP-TEAD Inhibitor 1 (Peptide 17)

A1149-1 1 mg
EUR 282

ET-1 Polyclonal Conjugated Antibody

C41562 100ul
EUR 476.4

Porcine ET-1 ELISA Kit

EPE0184 96Tests
EUR 625.2

Rabbit ET-1 ELISA Kit

ERTE0184 96Tests
EUR 625.2

Rat ET-1 ELISA Kit

ERE0184 96Tests
EUR 625.2

Mouse ET-1 ELISA Kit

EME0184 96Tests
EUR 625.2

Human ET-1 ELISA Kit

EHE0184 96Tests
EUR 625.2

Goat ET-1 ELISA Kit

EGTE0184 96Tests
EUR 625.2

Bovine ET-1 ELISA Kit

EBE0184 96Tests
EUR 625.2

Canine ET-1 ELISA Kit

ECE0184 96Tests
EUR 625.2

Anserini ET-1 ELISA Kit

EAE0184 96Tests
EUR 625.2

Canine ET-1 ELISA Kit

ELA-E0482d 96 Tests
EUR 1113.6

Big ET/ Rat Big ET ELISA Kit

ELA-E0483r 96 Tests
EUR 1063.2

ET-1(Endothelin-1) ELISA Kit

EU0205 96T
EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: General;Sensitivity: 0.625pg/ml

p21/Cyclin-Dependent Kinase Inhibitor 1

MO47036 100 ul
EUR 418.8

NFAT Inhibitor

A4539-1 1 mg
EUR 165.6
Description: Selective inhibitor of calcineurin-mediated dephosphorylation of nuclear factor of activated T cells (NFAT). Does not disrupt other calcineurin-dependent pathways. Inhibits NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells.

Lck Inhibitor

A3539-1 1 mg
EUR 184.8
Description: Lck Inhibitor is a small-molecule inhibitor of with IC50 value of 7 nM [1].The lymphocyte specific kinase which expressed in NK cells and T-cells is a member of the Src kinase family.

EGFR Inhibitor

C3327-1 1 mg
EUR 184.8
Description: EGFR inhibitor is a cell permeable, pyrimidine compound that selectively inhibits the EGFR kinase with IC50 value of 21 nM [1]. EGFR is a transmembrane protein, and is a receptor for members of epidermal growth factor family.

Stat5 Inhibitor

9484-1 each
EUR 144

Chk2 Inhibitor

1702-1 each
EUR 216

SCD1 Inhibitor

1716-1 each
EUR 261.6

ACC2 Inhibitor

1717-1 each
EUR 261.6

Syk Inhibitor

1983-1 each
EUR 151.2

Apoptosis Inhibitor

27734-1 10 mg
EUR 150
Description: Apoptosis Inhibitor is a cell-permeable inhibitor of apoptosis induction. It does not directly inhibit caspase-3, but its effects are attributable to the inhibition of caspase-3 activation.

Phosphatase Inhibitor Cocktail 1 (100X in DMSO)

K1012-1 1 ml
EUR 122.4

Human Cyclin-dependent kinase inhibitor 1(CDKN1A) ELISA kit

1-CSB-EL005086HU
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Cyclin-dependent kinase inhibitor 1(CDKN1A) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Cyclin-dependent kinase inhibitor 1(CDKN1A) ELISA kit

1-CSB-EL005086MO
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Cyclin-dependent kinase inhibitor 1(CDKN1A) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

ET-2 Antibody

35400-100ul 100ul
EUR 468

ET-3 antibody

22579-100ul 100ul
EUR 468

Diacylglycerol Kinase Inhibitor I

50R-R59022 50 mg
EUR 289.2
Description: Diacylglycerol Kinase Inhibitor I chemical reference substance

Aurora Kinase Inhibitor III

B7947-.5 500 µg
EUR 141.6
Description: Aurora Kinase Inhibitor III

Aurora Kinase Inhibitor III

B7947-5 5 mg
EUR 714
Description: Aurora Kinase Inhibitor III

Adenosine Kinase Inhibitor (hydrate)

C5282-10 10 mg
EUR 435.6
Description: IC50: 1.7 nM in cell-free assaysAdenosine Kinase Inhibitor is an inhibitor of adenosine kinase. Adenosine kinase is the key metabolizing enzyme regulating cellular adenosine concentrations.

Adenosine Kinase Inhibitor (hydrate)

C5282-5 5 mg
EUR 360
Description: IC50: 1.7 nM in cell-free assaysAdenosine Kinase Inhibitor is an inhibitor of adenosine kinase. Adenosine kinase is the key metabolizing enzyme regulating cellular adenosine concentrations.

DiscoveryProbe? Kinase Inhibitor Library

L1024-.25 250 uL/well(10 mM solution)
EUR 13394.4

DiscoveryProbe? Kinase Inhibitor Library

L1024-5 5 mg/well
EUR 17473.2

RIP2 kinase inhibitor 2

HY-19761 50mg
EUR 2539.2

Aurora Kinase Inhibitor 3

HY-112373 1mg
EUR 198

Apigenin (Protein kinase inhibitor)

SIH-249-10MG 10 mg
EUR 127.2
Description: The substance Apigenin is a protein kinase inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is white solid which is soluble to 50 mM in DMSO.

Apigenin (Protein kinase inhibitor)

SIH-249-50MG 50 mg
EUR 255.6
Description: The substance Apigenin is a protein kinase inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is white solid which is soluble to 50 mM in DMSO.

Staurosporine (Protein kinase inhibitor)

SIH-253-1MG 1 mg
EUR 380.4
Description: The substance Staurosporine is a protein kinase inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is pale yellow solid which is soluble to 50 mM in DMSO.

Staurosporine (Protein kinase inhibitor)

SIH-253-250UG 250 µg
EUR 178.8
Description: The substance Staurosporine is a protein kinase inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is pale yellow solid which is soluble to 50 mM in DMSO.

6BIO (PDK1 kinase inhibitor)

SIH-422-25MG 25 mg
EUR 474
Description: The substance 6BIO is a pdk1 kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is dark red solid which is soluble to 10 mM in DMSO and to 10 mM in ethanol.

6BIO (PDK1 kinase inhibitor)

SIH-422-5MG 5 mg
EUR 178.8
Description: The substance 6BIO is a pdk1 kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is dark red solid which is soluble to 10 mM in DMSO and to 10 mM in ethanol.

AG1296 (PDGFR kinase inhibitor)

SIH-426-25MG 25 mg
EUR 608.4
Description: The substance AG1296 is a pdgfr kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is off-white to brownish solid which is soluble in DMSO or dichloromethane.

AG1296 (PDGFR kinase inhibitor)

SIH-426-5MG 5 mg
EUR 205.2
Description: The substance AG1296 is a pdgfr kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is off-white to brownish solid which is soluble in DMSO or dichloromethane.

CHIR99021 (GSK3? kinase inhibitor)

SIH-437-1MG 1 mg
EUR 151.2
Description: The substance CHIR99021 is a gsk3? kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white to light brown solid which is soluble to 20 mM in DMSO.

CHIR99021 (GSK3? kinase inhibitor)

SIH-437-5MG 5 mg
EUR 246
Description: The substance CHIR99021 is a gsk3? kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white to light brown solid which is soluble to 20 mM in DMSO.

Dorsomorphin (AMPK kinase inhibitor)

SIH-443-25MG 25 mg
EUR 514.8
Description: The substance Dorsomorphin is a ampk kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is yellow solid which is soluble in DMSO (4 mg/ml, warm).

Dorsomorphin (AMPK kinase inhibitor)

SIH-443-5MG 5 mg
EUR 184.8
Description: The substance Dorsomorphin is a ampk kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is yellow solid which is soluble in DMSO (4 mg/ml, warm).

Gefitinib (EGFR Kinase inhibitor)

SIH-445-250MG 250 mg
EUR 360
Description: The substance Gefitinib is a egfr kinase inhibitor. It is synthetically produced and has a purity of >99%. The pure substance is solid which is soluble in DMSO (89 mg/ml at 25 °C), methanol (20 mg/ml), ethanol (4 mg/ml at 25 °C), DMF (20 mg/ml), and water (<1 mg/ml at 25 °C).

Gefitinib (EGFR Kinase inhibitor)

SIH-445-50MG 50 mg
EUR 164.4
Description: The substance Gefitinib is a egfr kinase inhibitor. It is synthetically produced and has a purity of >99%. The pure substance is solid which is soluble in DMSO (89 mg/ml at 25 °C), methanol (20 mg/ml), ethanol (4 mg/ml at 25 °C), DMF (20 mg/ml), and water (<1 mg/ml at 25 °C).

Genistein (Tyrosine kinase inhibitor)

SIH-446-10MG 10 mg
EUR 117.6
Description: The substance Genistein is a tyrosine kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is creamy off-white solid which is soluble in DMSO (30 mg/ml), 100% ethanol (4 mg/ml) or dilute aqueous base; insoluble in water.

Genistein (Tyrosine kinase inhibitor)

SIH-446-50MG 50 mg
EUR 198
Description: The substance Genistein is a tyrosine kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is creamy off-white solid which is soluble in DMSO (30 mg/ml), 100% ethanol (4 mg/ml) or dilute aqueous base; insoluble in water.

GF109203X (PKC kinase inhibitor)

SIH-447-10MG 10 mg
EUR 306
Description: The substance GF109203X is a pkc kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is red solid which is soluble in dimethyl formamide or DMSO (10 mg/ml, warm to 40°C and vortex well).

GF109203X (PKC kinase inhibitor)

SIH-447-1MG 1 mg
EUR 178.8
Description: The substance GF109203X is a pkc kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is red solid which is soluble in dimethyl formamide or DMSO (10 mg/ml, warm to 40°C and vortex well).

GW2580 (cFMS kinase inhibitor)

SIH-449-25MG 25 mg
EUR 447.6
Description: The substance GW2580 is a cfms kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white to beige solid which is soluble in DMSO: 10 mg/ml, clear (warmed) .

GW2580 (cFMS kinase inhibitor)

SIH-449-5MG 5 mg
EUR 168
Description: The substance GW2580 is a cfms kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white to beige solid which is soluble in DMSO: 10 mg/ml, clear (warmed) .

Imatinib mesylate (Kinase inhibitor)

SIH-453-100MG 100 mg
EUR 279.6
Description: The substance Imatinib mesylate is a kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white to beige solid which is soluble H2O: soluble10 mg/ml, clear .

Imatinib mesylate (Kinase inhibitor)

SIH-453-20MG 20 mg
EUR 151.2
Description: The substance Imatinib mesylate is a kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white to beige solid which is soluble H2O: soluble10 mg/ml, clear .

KT5720 (PKA kinase inhibitor)

SIH-457-100UG 100 µg
EUR 246
Description: The substance KT5720 is a pka kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white powder which is soluble in methanol: clear colorless solution at 5 mg/ml.

KT5720 (PKA kinase inhibitor)

SIH-457-500UG 500 µg
EUR 682.8
Description: The substance KT5720 is a pka kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white powder which is soluble in methanol: clear colorless solution at 5 mg/ml.

LYS6K2 (S6 kinase inhibitor)

SIH-462-25MG 25 mg
EUR 582
Description: The substance LYS6K2 is a s6 kinase inhibitor. It is synthetically produced and has a purity of 0.97. The pure substance is yellow solid which is soluble in DMSO (up to 1 mg/ml) or DMF (up to 3 mg/ml with warming).

LYS6K2 (S6 kinase inhibitor)

SIH-462-5MG 5 mg
EUR 205.2
Description: The substance LYS6K2 is a s6 kinase inhibitor. It is synthetically produced and has a purity of 0.97. The pure substance is yellow solid which is soluble in DMSO (up to 1 mg/ml) or DMF (up to 3 mg/ml with warming).

PD98059 (MEK kinase inhibitor)

SIH-466-25MG 25 mg
EUR 514.8
Description: The substance PD98059 is a mek kinase inhibitor. It is synthetically produced and has a purity of ?95%. The pure substance is pale yellow solid which is soluble in DMSO (6.5 mg/ml); 25 mg/ml in anhydrous DMSO), methanol, dichlormethane and 100% ethanol (0.6 mg/ml).

PD98059 (MEK kinase inhibitor)

SIH-466-5MG 5 mg
EUR 184.8
Description: The substance PD98059 is a mek kinase inhibitor. It is synthetically produced and has a purity of ?95%. The pure substance is pale yellow solid which is soluble in DMSO (6.5 mg/ml); 25 mg/ml in anhydrous DMSO), methanol, dichlormethane and 100% ethanol (0.6 mg/ml).

PP1 (Src kinase inhibitor)

SIH-469-25MG 25 mg
EUR 742.8
Description: The substance PP1 is a src kinase inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is tan solid which is soluble in DMSO (25 mg/ml), slightly soluble in 100% ethanol.

PP1 (Src kinase inhibitor)

SIH-469-5MG 5 mg
EUR 246
Description: The substance PP1 is a src kinase inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is tan solid which is soluble in DMSO (25 mg/ml), slightly soluble in 100% ethanol.

PP2 (Src kinase inhibitor)

SIH-470-25MG 25 mg
EUR 884.4
Description: The substance PP2 is a src kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is off-white solid which is soluble in DMSO (25 mg/ml).

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